Ebastine Tablets I.P. 20mg – Antihistamines such as ebastine tablets I.P. 20 mg constitute a second generation of medications. Their domain of operation covers those symptoms associated with allergic conditions. By virtue of being a non-sedating H₁ receptor antagonist, ebastine is helpful in relieving allergic rhinitis, urticaria (hives), and disorders of related types, without causing much sedation.
Composition
Active Ingredient: Ebastine 20 mg
Ebastine is quickly metabolized by the body to its active metabolite carebastine, which exhibits therapeutic action. The conversion thereby maintains effectiveness over an entire day.
How It Works
Ebastine acts by specifically inhibiting the peripheral H₁ receptors and thus blocking the actions of histamine, a factor responsible for the allergic symptom manifestation. These mostly include itching, swelling, redness, and pain arising in a matter of minutes heading into hours of an allergic reaction, with ebastine minimizing their intensity by blocking histamine from binding at the receptors.
Side Effects of Ebastine
Common side effects may include
- Headache
- Dry mouth
- Drowsiness
- Pharyngitis
- Abdominal pain
- Heartburn
- Weakness
- Nosebleed
- Nausea
- Insomnia
Most side effects tend to be mild or transient. If any adverse reactions persist or worsen, the patient should immediately consult a physician.
Precautions of Ebastine
Hypersensitivity: Should not be used in patients who are known to be hypersensitive to this preparation or any component thereof.
Liver Impairment: Exercise caution in patients with liver impairment. Dose adjustment may be considered.
Pregnancy and lactation: Breastfeeding or pregnant women should first consult a physician before taking the drug.
Drug Interactions: Increases plasma levels of Ebastine and may predispose the patient to QTc interval prolongation, when given concomitantly with ketoconazole or itraconazole or clarithromycin or erythromycin. Such combinations should be avoided unless absolutely necessary and on the advice of a physician.
